Fig. 1 · Structure
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Epsilon-(gamma-glutamyl)-lysine
N(6)-acyl-L-lysine Derivative
Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative that serves as a substrate for tissue transglutaminase (tTg). This compound plays a crucial role in forming epsilon-(gamma-glutamyl)lysine cross-links between extracellular matrix (ECM) components, which are significant in various pathological conditions, including non-diabetic kidney disease and glaucoma filtration. It is valuable for studying ECM remodeling and the biochemical pathways involved in tissue repair and fibrosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 17105-15-6 |
| Applications | N(6)-acyl-L-lysine Derivative |
| Formula | C11H21N3O5 |
| Molecular Weight | 275.30 |
| Synonyms | H-Glu(H-Lys-OH)-OH; γ-Glu-ε-Lys |
| SMILES | OC([C@@H](N)CCC(NCCCC[C@H](N)C(O)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.