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ER ligand-6

ER Ligand

ER Ligand-6 is a ligand specifically targeting estrogen receptors (ER). It is utilized in the development of PROTAC-based degradation systems, such as PROTAC ER Degrader-14, facilitating the controlled degradation of ER proteins. This compound exhibits key biological activity in modulating estrogen receptor signaling pathways and is of particular interest in research focused on hormone-dependent cancers and cellular responses to estrogen.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2504914-79-6
Applications	ER Ligand
Formula	C₂₉H₃₂FNO₄
Molecular Weight	477.57
SMILES	FC1=C(N2CCC(CC2)C(OC)OC)C=CC([C@@H]3C4=CC=C(O)C=C4OC[C@@H]3C5=CC=CC=C5)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.