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ER ligand-8

ER Ligand

ER ligand-8 is a potent ligand for the estrogen receptor (ER), playing a crucial role in estrogen signaling pathways. It is utilized in the synthesis of the PROTAC molecule ERD-1233, which facilitates targeted protein degradation. This compound is valuable in studies focusing on hormone-responsive cancers and provides insights into estrogen receptor modulation and its associated therapeutic implications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2229713-97-5
Applications	ER Ligand
Formula	C₃₀H₂₇F₉O₄S
Molecular Weight	654.58
SMILES	O=S(OC1=CC=C([C@H]2[C@@H](C3=CC=CC=C3)CCC4=C2C=CC(OC(C)(C)C)=C4)C=C1)(C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.