Fig. 1 · Structure
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ER176
TSPO Ligand
ER176 is a novel PET radioligand targeting the 18 kDa translocator protein (TSPO), a key biomarker associated with neuroinflammation. Its high specificity and affinity for TSPO make it an essential tool in the imaging of neuroinflammatory processes, enabling researchers to investigate various neurological disorders. ER176 is particularly valuable for studies focused on the role of neuroinflammation in conditions such as Alzheimer's disease and multiple sclerosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 1373887-29-6 |
| Applications | TSPO Ligand |
| Formula | C20H20ClN3O |
| Molecular Weight | 353.85 |
| Synonyms | BIBD-239 |
| SMILES | O=C(C1=NC(C2=CC=CC=C2Cl)=C3C=CC=CC3=N1)N(C)[C@H](C)CC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.