Fig. 1 · Structure

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ERα ligand 4

ERα Ligand

ERα ligand 4 is a high-affinity ligand targeting estrogen receptor alpha (ERα). It serves as a crucial component in the synthesis of PROTACs, including the compound NEP168, which facilitates targeted protein degradation. This compound is valuable for studying ERα-mediated signaling pathways and advancing research in cancer biology and hormone-related diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 97818-93-4
Applications ERα Ligand
Formula C24H22O3
Molecular Weight 358.43
SMILES
OC(COC1=CC=C(/C(C2=CC=CC=C2)=C(CC)\C3=CC=CC=C3)C=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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