Documents & Downloads

Eratrectinib

Trk Inhibitor

Eratrectinib is a selective Trk inhibitor that targets tropomyosin receptor kinases involved in various signaling pathways. This compound demonstrates significant biological activity against cancers associated with Trk alterations, making it a valuable tool for studying tropomyosin receptor kinase-related diseases. Researchers can utilize Eratrectinib to explore its therapeutic potential in oncology and to investigate the underlying mechanisms of Trk-driven tumors.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2396516-98-4
Applications	Trk Inhibitor
Formula	C₂₁H₂₂FN₇O
Molecular Weight	407.44
SMILES	FC(C=C1[C@]2([H])N(CCC2)C3=NC4=C5C=NN4C=C3)=CN=C1CCN(C6CC6)NC5=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.