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ERCC1/XPA interaction inhibitor 1

ERCC1/XPA Interaction Inhibitor

ERCC1/XPA Interaction Inhibitor 1 is a potent inhibitor targeting the interaction between ERCC1 and XPA, with an EC50 value of 4.7 µM. This compound is valuable for studying DNA damage response pathways and may facilitate the exploration of resistance mechanisms to platinum-based chemotherapy agents. Its ability to disrupt the ERCC1/XPA complex makes it a significant tool for research into cancer therapy and the development of strategies to enhance treatment efficacy.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3078058-57-5
Applications	ERCC1/XPA Interaction Inhibitor
Formula	C₂₄H₂₂ClN₃O₂S
Molecular Weight	451.97
SMILES	O=C(NC1=CC=CC=C1C(O)CSC2=NC(C)=CC(C)=C2C#N)CC3=CC=C(Cl)C=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.