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Biological Activity
ERD-308 is a highly potent PROTAC degrader of estrogen receptor (ER) for ER positive breast cancer treatment.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 9.96 mL | 49.79 mL | 99.58 mL |
| 0.5 mM | 1.99 mL | 9.96 mL | 19.92 mL |
| 1 mM | 1 mL | 4.98 mL | 9.96 mL |
| 5 mM | 0.2 mL | 1 mL | 1.99 mL |
*The above data is based on the productmolecular weight 1004.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18446 |
|---|---|
| Actions | Degrader |
| CAS No. | 2320561-35-9 |
| Formula | C55H65N5O9S2 |
| M. Wt | 1004.26 |
| Purity | >98% |
| Synonyms | ERD308, ERD 308 |
| SMILES | O=C(C1=C(C2=CC=C(O)C=C2)SC3=CC(O)=CC=C13)C4=CC=C(OCCN(CCCCCOCC(N[[email protected]@H](C(C)(C)C)C(N5[[email protected]](C(N[[email protected]@H](C)C6=CC=C(C7=C(C)N=CS7)C=C6)=O)C[[email protected]@H](O)C5)=O)=O)CC)C=C4 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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