Fig. 1 · Structure
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Eriodictyol chalcone
Antioxidant
Eriodictyol chalcone is an antioxidant compound primarily targeting various key enzymes, including 5-LOX (IC50 = 0.043 µM), aromatase/CYP19A1 (IC50 = 2.8 µM), PTPase 1B (IC50 = 1.26 µM), and COX (IC50 = 34 µM). It demonstrates significant free radical scavenging activity and has been shown to inhibit the growth of plasmodia while enhancing the efficacy of Artemisinin. Additionally, Eriodictyol chalcone has potential therapeutic applications in alleviating depression-like behaviors in animal models and may be explored for its effects on breast cancer and related diseases. This compound also serves as a biosynthetic precursor for Aureusidin, making it valuable in research on malaria and depression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 14917-41-0 |
| Applications | Antioxidant |
| Formula | C15H12O6 |
| Molecular Weight | 288.25 |
| SMILES | O=C(C1=C(O)C=C(O)C=C1O)/C=C/C2=CC=C(O)C(O)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.