Fig. 1 · Structure
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Eritadenine
AdoHcyase Inhibitor
Eritadenine is a potent inhibitor of adenosylhomocysteine hydrolase (AdoHcyase), demonstrating an IC50 value of 7 nM. This acyclic sugar adenosine analogue has shown significant inhibitory activity against the growth of Cryptosporidium parvum, with an MIC50 of 3 μM. Eritadenine is valuable for research applications in colorectal adenocarcinoma, aiding investigations into metabolic pathways and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 23918-98-1 |
| Applications | AdoHcyase Inhibitor |
| Formula | C9H11N5O4 |
| Molecular Weight | 253.21 |
| Synonyms | Lentinacin; D-Eritadenine; Lentysine |
| SMILES | O=C([C@@H]([C@@H](CN1C=NC2=C(N=CN=C12)N)O)O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.