Fig. 1 · Structure
Documents & Downloads
ERK-IN-8
ERK Inhibitor
ERK-IN-8 is an aniline pyrimidine derivative that functions as a selective inhibitor of ERK2. It demonstrates potent inhibitory activity with an IC50 of ≤50 nM in vitro. This compound is valuable for applications in cancer research, enabling investigations into ERK signaling pathways and their roles in tumorigenesis.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2226293-75-8 |
| Applications | ERK Inhibitor |
| Formula | C26H29N7O2 |
| Molecular Weight | 471.55 |
| SMILES | C=CC(NC1=CC(NC2=NC=CC(C3=CNC4=C3C=CC=C4)=N2)=C(OC)C=C1N(C)CCNC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.