Fig. 1 · Structure
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ERK1/2 inhibitor 8
ERK Inhibitor
ERK1/2 inhibitor 8 is a potent inhibitor of extracellular signal-regulated kinases (ERK) with an IC50 value of 0.48 nM specifically targeting ERK2. This compound is valuable for research applications involving cellular signaling pathways, especially those related to cancer and inflammation. Its high potency makes it an essential tool for elucidating ERK-mediated biological processes and developing therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2648368-43-6 |
| Applications | ERK Inhibitor |
| Formula | C23H20ClN7O2S |
| Molecular Weight | 493.97 |
| SMILES | O=C1C2=C(C3(COC3)N1CC4=CC(Cl)=CC=C4)SC(C5=C(C)C=NC(NC6=CC=NN6C)=N5)=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.