Fig. 1 · Structure
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Erucamide
TMEM19 Ligand, T3SS Inhibitor
Erucamide is a TMEM19 ligand and an effective inhibitor of type III secretion system (T3SS) in Gram-negative bacteria. This compound demonstrates neuroprotective effects in retinal degeneration models and mitigates anxiety- and depression-like behaviors in mice. By binding to the hydrophobic pocket of HrcC, erucamide disrupts outer membrane localization and inhibits effector protein secretion in pathogenic bacteria. Its applications extend to research on retinitis pigmentosa, mood disorders, and plant-pathogen interactions, making it a valuable tool in pharmacological and microbiological studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 112-84-5 |
| Applications | TMEM19 Ligand, T3SS Inhibitor |
| Formula | C22H43NO |
| Molecular Weight | 337.58 |
| Synonyms | cis-13-Docosenamide |
| SMILES | CCCCCCCC/C=C\CCCCCCCCCCCC(N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.