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ERX-208

LIPA Binder

ERX-208 is a potent inhibitor of lysosomal acid lipase A (LIPA) that induces endoplasmic reticulum stress, driving apoptosis in cancer cells. This reagent demonstrates significant biological activity in ovarian cancer, making it a valuable tool for research focused on cancer therapies and mechanisms of cell death. Its role in modulating lipid metabolism and promoting cellular stress responses provides insights into potential therapeutic strategies against cancer progression.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2440087-57-8
Applications	LIPA Binder
Formula	C₄₇H₅₂N₆O₁₀
Molecular Weight	860.95
SMILES	OCCOC1=C([N+]([O-])=O)C=CC(C(NC(C(OCC(C)C)=C2)=CC=C2C(NC3=C(OCC(C)C)C=C(C(N[C@@H]4CC[C@@H](C(NC5=CN=C(C=CC=C6)C6=C5)=O)CC4)=O)C=C3)=O)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.