Documents & Downloads

ESC1002755

Name: ESC1002755
Brand: Adooq Bioscience
SKU: A69088
Availability: OutOfStock

Cat. No. A69088 CAS 2915567-21-2

17β-HSD10 Inhibitor

ESC1002755 is a selective inhibitor of 17β-HSD10, exhibiting an IC50 of 19 nM and demonstrating non-competitive inhibition against the cofactor NADH. This compound shows minimal cytotoxicity in HEK293 cells at a concentration of 50 μM, making it a promising tool for studies related to Alzheimer’s disease and hormone-dependent cancers, including prostate, bone, and colorectal cancer. Research applications include exploring the enzymatic mechanisms and therapeutic interventions associated with these conditions.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2915567-21-2
Applications	17β-HSD10 Inhibitor
Formula	C₂₁H₁₈ClNO₂S
Molecular Weight	383.89
SMILES	O=C(N1CCC[C@H]1C2=C(C=CC=C2)C3=CC(O)=CC=C3)C4=C(C=CS4)Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.