(-)-Eseroline fumarate is a potent 5-HT receptor antagonist that effectively disrupts cellular activities in various biological systems. It is known to induce cell death by promoting the release of adenine nucleotides and 5-hydroxytryptamine (5-HT) from neuronal cells, alongside eliciting lactic acid dehydrogenase (LDH) leakage from cancer cells. Additionally, (-)-Eseroline fumarate inhibits electrically evoked contractions in the mouse vas deferens and guinea pig ileum, making it a valuable tool for investigating neuropharmacological effects and potential therapeutic applications in cancer research.
(-)-Eseroline fumarate is a potent 5-HT receptor antagonist that effectively disrupts cellular activities in various biological systems. It is known to induce cell death by promoting the release of adenine nucleotides and 5-hydroxytryptamine (5-HT) from neuronal cells, alongside eliciting lactic acid dehydrogenase (LDH) leakage from cancer cells. Additionally, (-)-Eseroline fumarate inhibits electrically evoked contractions in the mouse vas deferens and guinea pig ileum, making it a valuable tool for investigating neuropharmacological effects and potential therapeutic applications in cancer research.
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