Fig. 1 · Structure
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Estradiol benzoate
HBx inhibitor
Estradiol benzoate (β-Estradiol 3-benzoate) acts as an HBx protein inhibitor, effectively reducing androgen and hepatitis B virus (HBV) transcription and replication. Additionally, it exhibits antifertility properties and demonstrates activity against Toxoplasma gondii. Research suggests that Estradiol benzoate may also enhance memory behavior in ovariectomized female mice, making it a valuable tool for studies related to reproductive biology and neurocognition.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 50-50-0 |
| Applications | HBx inhibitor |
| Formula | C25H28O3 |
| Molecular Weight | 376.49 |
| Synonyms | β-Estradiol 3-benzoate; 17β-Estradiol 3-benzoate |
| SMILES | C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=CC(OC(C5=CC=CC=C5)=O)=C4)[C@@]3([H])CC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.