Fig. 1 · Structure
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Etavopivat
Cat. No.
A77402
CAS
2245053-57-8
Pyruvate Kinase Activator
Etavopivat is a selective erythrocyte pyruvate kinase (PKR) activator that enhances glycolytic flux in red blood cells. It exhibits significant antisickling effects, making it a valuable tool for investigating sickle cell disease and other hemoglobinopathies. This compound is of interest in research aimed at improving red blood cell function and mitigating the complications associated with abnormal hemoglobin disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 2245053-57-8 |
| Applications | Pyruvate Kinase Activator |
| Formula | C22H23N3O6S |
| Molecular Weight | 457.50 |
| Synonyms | FT-4202 |
| SMILES | O=S(N1CC2=C(CN(C2)C([C@@H](C3=CC=CC=C3)CO)=O)C1)(C4=CN=C(OCCO5)C5=C4)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.