Fig. 1 · Structure
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Ethoxysanguinarine
CIP2A Inhibitor
Ethoxysanguinarine is a benzophenanthridine alkaloid derived from Macleaya cordata, acting primarily as an inhibitor of the protein phosphatase 2A (CIP2A). This compound demonstrates significant biological activity by inducing apoptosis in colorectal cancer cells and inhibiting their proliferation. Ethoxysanguinarine is valuable for research applications focused on cancer biology and therapeutic strategies targeting CIP2A.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 28342-31-6 |
| Applications | CIP2A Inhibitor |
| Formula | C22H19NO5 |
| Molecular Weight | 377.39 |
| SMILES | CN1C2=C3C(C=C4OCOC4=C3)=CC=C2C5=C(C6=C(OCO6)C=C5)C1OCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.