Fig. 1 · Structure
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Ethyl β-carboline-3-carboxylate
Short-acting Benzodiazepine Receptor Antagonist
Ethyl β-carboline-3-carboxylate is a short-acting antagonist of benzodiazepine receptors, functioning primarily by competing for binding sites on these receptors. This compound does not alter cerebellar cGMP levels in isolation; however, it significantly inhibits the cGMP increase induced by Diazepam in co-administration studies. Ethyl β-carboline-3-carboxylate serves as a valuable tool in researching the pharmacology of benzodiazepines and understanding their mechanisms of action in neuronal signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 74214-62-3 |
| Applications | Short-acting Benzodiazepine Receptor Antagonist |
| Formula | C14H12N2O2 |
| Molecular Weight | 240.26 |
| SMILES | O=C(C1=CC2=C(C=N1)NC3=C2C=CC=C3)OCC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.