Fig. 1 · Structure
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Ethyl gentisate
ALP Activator
Ethyl gentisate (Ethyl 2,5-dihydroxybenzoate) is an activator of alkaline phosphatase (ALP) that facilitates cell differentiation. It promotes osteogenic differentiation in human mesenchymal stem cells (hMSCs) while inhibiting RANKL-induced osteoclastogenesis in RAW264.7 cells, thereby contributing to the regulation of bone remodeling. This compound is valuable for research applications focused on bone biology and regenerative medicine.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 3943-91-7 |
| Applications | ALP Activator |
| Formula | C9H10O4 |
| Molecular Weight | 182.17 |
| Synonyms | Ethyl 2,5-dihydroxybenzoate |
| SMILES | OC1=C(C=C(C=C1)O)C(OCC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.