Fig. 1 · Structure
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Ethyl-L-NIO hydrochloride
DDAH-1 Inhibitor
Ethyl-L-NIO hydrochloride is a selective inhibitor of human dimethylarginine dimethylaminohydrolase 1 (hDDAH-1), exhibiting a competitive inhibition profile with an IC50 of 70 μM and a Ki of 32 μM. This compound is valuable for investigating the role of DDAH-1 in nitric oxide metabolism and may enhance understanding of cardiovascular disease mechanisms. Its application in research can elucidate the biochemical pathways involving asymmetric dimethylarginine regulation and related signaling processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 150403-97-7 |
| Applications | DDAH-1 Inhibitor |
| Formula | C9H20ClN3O2 |
| Molecular Weight | 237.73 |
| SMILES | OC([C@@H](N)CCCNC(CCC)=N)=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.