Ethylmalonic acid-d5 is a deuterated form of ethylmalonic acid, serving as a stable isotope for research applications. This short-chain organic dicarboxylic acid is known to synergistically induce mitochondrial permeability transition in conjunction with Ca2+, inhibit mitochondrial creatine kinase (Mi-CK), and disrupt mitochondrial energy metabolism. Ethylmalonic acid-d5 is valuable in studying disorders such as short-chain acyl-CoA dehydrogenase deficiency (SCADD) and other genetic metabolic diseases associated with the accumulation of ethylmalonic acid.
Ethylmalonic acid-d5 is a deuterated form of ethylmalonic acid, serving as a stable isotope for research applications. This short-chain organic dicarboxylic acid is known to synergistically induce mitochondrial permeability transition in conjunction with Ca2+, inhibit mitochondrial creatine kinase (Mi-CK), and disrupt mitochondrial energy metabolism. Ethylmalonic acid-d5 is valuable in studying disorders such as short-chain acyl-CoA dehydrogenase deficiency (SCADD) and other genetic metabolic diseases associated with the accumulation of ethylmalonic acid.
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