Etomoxir (sodium salt)

Catalog No.: A11415

CPT-1 irreversible inhibitor

Etomoxir (sodium salt)

Etomoxir (sodium salt) Chemical Structure

CAS NO. 828934-41-4 (sodium salt), 124083-20-1 (Base)

Etomoxir is an inhibitor of carnitine palmitoyltransferase A (CPT1), which is required for the oxidation of long-chain acyl CoA esters. Also a strong inhibitor of mitochondrial CPT1 and a candidate as an anti-diabetic drug.

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5 mg

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10 mg

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25 mg

Regular Price: $240.00

Special Price $192.00

50 mg

Regular Price: $420.00

Special Price $336.00

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  • A. Geneste, .et al. Adipocyte-conditioned medium induces resistance of breast cancer cells to lapatinib, BMC Pharmacol Toxicol, 2020, 21: 61 PMID: 32795383

Biological Activity

Etomoxir is an inhibitor of carnitine palmitoyltransferase A (CPT1), which is required for the oxidation of long-chain acyl CoA esters. Also a strong inhibitor of mitochondrial CPT1 and a candidate as an anti-diabetic drug.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.18 mL 155.89 mL 311.78 mL
0.5 mM 6.24 mL 31.18 mL 62.36 mL
1 mM 3.12 mL 15.59 mL 31.18 mL
5 mM 0.62 mL 3.12 mL 6.24 mL

*The above data is based on the productmolecular weight 320.74. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11415
Actions Inhibitor
CAS No. 828934-41-4 (sodium salt), 124083-20-1 (Base)
Formula C15H18ClO4.Na
M. Wt 320.74
Purity >98%
Synonyms (R)-(+)-Etomoxir
SMILES C1[[email protected]](O1)(CCCCCCOC2=CC=C(C=C2)Cl)C(=O)[O-].[Na+]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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