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Biological Activity
ETP-46321 is a potent and orally bioavailable PI3K α/δ inhibitor with potent biochemical and cellular activity and good pharmacokinetic properties (PK) after oral dosing.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.12 mL | 105.59 mL | 211.17 mL |
| 0.5 mM | 4.22 mL | 21.12 mL | 42.23 mL |
| 1 mM | 2.11 mL | 10.56 mL | 21.12 mL |
| 5 mM | 0.42 mL | 2.11 mL | 4.22 mL |
*The above data is based on the productmolecular weight 473.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16271 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1252594-99-2 |
| Formula | C20H27N9O3S |
| M. Wt | 473.55 |
| Purity | >98% |
| Synonyms | ETP46321, ETP 46321 |
| SMILES | NC1=NC=C(C2=CN3C(C(N4CCOCC4)=N2)=NC(CN5CCN(S(=O)(C)=O)CC5)=C3)C=N1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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