Fig. 1 · Structure
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Evariquinone
Neuroprotective Agent
Evariquinone is an anthraquinone compound with neuroprotective properties derived from the endophytic fungus Colletotrichum sp. JS-0367 of mulberry. It exhibits direct antioxidant activity by inhibiting excessive phosphorylation of the JNK, ERK1/2, and p38 MAPK signaling pathways, ultimately reducing neuronal apoptosis through suppression of reactive oxygen species (ROS) and calcium ion (Ca2+) levels. Evariquinone is a valuable tool for investigating neurological disorders related to glutamate excitotoxicity, including Alzheimer's disease, Parkinson's disease, and cerebral ischemia.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 594860-23-8 |
| Applications | Neuroprotective Agent |
| Formula | C16H12O6 |
| Molecular Weight | 300.26 |
| SMILES | O=C1C2=C(C(C3=CC(O)=C(C(O)=C13)O)=O)C=C(C=C2OC)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.