Fig. 1 · Structure

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Evazarsen

Angiotensinogen Synthesis Inhibitor

Evazarsen is an angiotensinogen synthesis inhibitor that effectively reduces the production of angiotensinogen, a precursor to angiotensin II, a peptide that plays a crucial role in blood pressure regulation. This compound exhibits antihypertensive properties, making it valuable for research focused on cardiovascular diseases and hypertension management. Its ability to modulate the renin-angiotensin system supports investigations into therapeutic strategies for hypertension and related disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2589926-22-5
Applications Angiotensinogen Synthesis Inhibitor
Formula C296H434N86O146P20S19
Molecular Weight 8761.80
Synonyms ISIS-757456

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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