Fig. 1 · Structure
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Evenamide
Sodium Channel Blocker
Evenamide is an orally available voltage-gated sodium channel blocker (Ki = 0.4 µM) primarily targeted for research in schizophrenia. It demonstrates efficacy across a variety of rodent models representing psychosis, mania, depression, and aggressive behavior. This compound serves as a valuable tool for investigating the underlying mechanisms of these psychiatric conditions and evaluating potential therapeutic interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Blocker |
| CAS Number | 1092977-61-1 |
| Applications | Sodium Channel Blocker |
| Formula | C16H26N2O2 |
| Molecular Weight | 278.39 |
| Synonyms | NW-3509 |
| SMILES | O=C(N(C)C)CNCCC1=CC=CC(OCCCC)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.