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- Renu Sudhakar, .et al. Bazedoxifene, a Postmenopausal Drug, Acts as an Antimalarial and Inhibits Hemozoin Formation, Microbiol Spectr, 2022, Jun 29;10(3) PMID: 35616371
Biological Activity
Raloxifene is an oral selective estrogen receptor modulator (SERM) that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women.
Targets
| ER | ||||
| 5.7 nM |
| In vitro (25°C) | DMSO | 90 mg/mL (176.45 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 1% methylcellulose | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.61 mL | 98.04 mL | 196.08 mL |
| 0.5 mM | 3.92 mL | 19.61 mL | 39.22 mL |
| 1 mM | 1.96 mL | 9.8 mL | 19.61 mL |
| 5 mM | 0.39 mL | 1.96 mL | 3.92 mL |
*The above data is based on the productmolecular weight 510. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10375 |
|---|---|
| CAS No. | 82640-04-8 |
| Formula | C28H28ClNO4S |
| M. Wt | 510 |
| Purity | >98% |
| SMILES | C1CCN(CC1)CCOC2=CC=C(C=C2)C(=O)C3=C(SC4=C3C=CC(=C4)O)C5=CC=C(C=C5)O.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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