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Biological Activity
EVP-6124 hydrochloride is a novel partial agonist of α7 neuronal nicotinic acetylcholine receptors (nAChRs). EVP-6124 showed selectivity for α7 nAChRs and did not activate or inhibit heteromeric α4β2 nAChRs.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.99 mL | 139.94 mL | 279.88 mL |
| 0.5 mM | 5.6 mL | 27.99 mL | 55.98 mL |
| 1 mM | 2.8 mL | 13.99 mL | 27.99 mL |
| 5 mM | 0.56 mL | 2.8 mL | 5.6 mL |
*The above data is based on the productmolecular weight 357.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15087 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 550999-74-1 |
| Formula | C16H18Cl2N2OS |
| M. Wt | 357.3 |
| Purity | >98% |
| Synonyms | EVP 6124 hydrochloride, EVP6124 hydrochloride |
| SMILES | C1CN2CCC1C(C2)NC(=O)C3=CC4=C(S3)C(=CC=C4)Cl.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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