Fig. 1 · Structure
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Exatecan-amide-CH2-O-CH2-CH2-OH
Exatecan Derivative
Exatecan-amide-CH2-O-CH2-CH2-OH is a derivative of the camptothecin analog Exatecan, functioning primarily as a topoisomerase I inhibitor. This compound exhibits significant anti-proliferative activity, making it a valuable tool for investigating cell proliferative disorders, particularly in cancer research. Its unique structure enables the exploration of therapeutic strategies aimed at disrupting cancer cell growth and survival.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2920907-39-5 |
| Applications | Exatecan Derivative |
| Formula | C28H28FN3O7 |
| Molecular Weight | 537.54 |
| SMILES | OCCOCC(N[C@@H]1C2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(F)=C(C)C(CC1)=C62)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.