Fig. 1 · Structure
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Exatecan analogue 1
Exatecan Analogue
Exatecan analogue 1 is a synthetic variant of Exatecan, designed to enhance the development of antibody-drug conjugates (ADCs). This compound has demonstrated potential in targeted cancer therapies, facilitating the delivery of cytotoxic agents specifically to tumor cells. Its structure allows for efficient integration into ADC formulations, thereby improving therapeutic efficacy while minimizing off-target effects.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2671770-58-2 |
| Applications | Exatecan Analogue |
| Formula | C23H20FN3O4 |
| Molecular Weight | 421.42 |
| SMILES | O=C1N2C(C(C(C2)=C3C4=C5CCC3)=NC4=CC(F)=C5N)=CC6=C1COC([C@]6(O)CC)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.