Fig. 1 · Structure
Documents & Downloads
Exatecan Intermediate 1
ADC Toxin
Exatecan Intermediate 1 is a key precursor in the synthesis of Exatecan, a potent inhibitor of DNA topoisomerase I. This compound exhibits significant anticancer activity, contributing to the development of antibody-drug conjugates (ADCs). Researchers can utilize Exatecan Intermediate 1 in studies focused on enhancing targeted cancer therapies and investigating mechanisms of resistance to topoisomerase inhibitors.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 110351-94-5 |
| Applications | ADC Toxin |
| Formula | C13H13NO5 |
| Molecular Weight | 263.25 |
| SMILES | O=C1[C@](O)(CC)C(C=C23)=C(CO1)C(N3CCC2=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.