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Exatecan Intermediate 4

Catalog No.: A41043
ADC Cytotoxin
Exatecan Intermediate 4, a key intermediate in the synthesis of Exatecan (DX-8951), functions as an ADC cytotoxin. This compound exhibits potent antitumor activity by disrupting DNA replication, leading to the inhibition of cancer cell proliferation. It is utilized in research related to various malignancies, including ovarian, lung, and breast cancers, providing insights into targeted cancer therapies and drug development.
Exatecan Intermediate 4 2436720-50-0 ADC Cytotoxin
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5mg
$20.00
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10mg
$30.00
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25mg
$60.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionExatecan Intermediate 4, a key intermediate in the synthesis of Exatecan (DX-8951), functions as an ADC cytotoxin. This compound exhibits potent antitumor activity by disrupting DNA replication, leading to the inhibition of cancer cell proliferation. It is utilized in research related to various malignancies, including ovarian, lung, and breast cancers, providing insights into targeted cancer therapies and drug development.
Product Information
Catalog NumA41043
FormulaC11H14ClFN2O
Molecular Weight244.70
CAS Number2436720-50-0
SMILESCC1=C2CCC(C(C2=C(C=C1F)N)=O)N.Cl
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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Antibody-drug Conjugates (ADC) > ADC Payload (ADC Cytotoxin)