Fig. 1 · Structure
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Exatecan-mpGly-Asn-Asn-(βAla)
Exatecan Derivative
Exatecan-mpGly-Asn-Asn-(βAla) is a derivative of Exatecan designed for targeted drug delivery applications. This compound serves as a linker for the synthesis of antibody-drug conjugates (ADCs), such as α-HER2_mpGlyAsnAsn(β-Ala)_Exatecan, enhancing therapeutic efficacy against specific tumors. Exatecan-mpGly-Asn-Asn-(βAla) is also applicable in various tumor research settings, facilitating studies aimed at understanding cancer biology and developing innovative treatment strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3076725-07-7 |
| Applications | Exatecan Derivative |
| Formula | C44H47FN10O13 |
| Molecular Weight | 942.90 |
| SMILES | O=C(C=CC1=O)N1CCC(NCC(N[C@@H](CC(N)=O)C(N[C@@H](CC(N)=O)C(NCCC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.