Fig. 1 · Structure
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Exo2
Secretion Inhibitor
Exo2 is an effective secretion inhibitor that interferes with the trafficking of Shiga toxin between endosomes and the trans-Golgi network. It prevents the exit of secretory cargo from the endoplasmic reticulum (ER) and disrupts Golgi apparatus function without altering trans-Golgi network morphology. Additionally, Exo2 has been shown to stimulate calcium-dependent exocytosis in permeabilized adrenal chromaffin cells, making it valuable for research involving cellular secretion pathways and vesicle transport mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 304684-77-3 |
| Applications | Secretion Inhibitor |
| Formula | C18H18N4O2S |
| Molecular Weight | 354.43 |
| SMILES | COC(C=C(C=C1)/C=N/NC2=C3C(CCCC4)=C4SC3=NC=N2)=C1O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.