Fig. 1 · Structure
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Exoenzyme C3, clostridium botulinum
Rho Inactivator
Exoenzyme C3 from Clostridium botulinum is a potent Rho inactivator that mono-ADP-ribosylates RhoA, B, and C, effectively inactivating these GTPases. This enzyme plays a crucial role in regulating cytoskeletal dynamics, inducing neuronal axonal and dendritic growth, and inhibiting macrophage migration. Exoenzyme C3 is valuable for research applications in spinal cord injury and diabetic painful neuropathy studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 58319-92-9 |
| Applications | Rho Inactivator |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.