Fig. 1 · Structure
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Exonuclease III
DNA Repair Enzyme
Exonuclease III is a DNA repair enzyme that specifically targets double-stranded DNA (dsDNA) and exhibits both apurinic/apyrimidinic (AP)-endonuclease and 3'→5' exonuclease activities. This enzyme facilitates the cleavage of single-stranded DNA (ssDNA) at the 5'-bond of phosphodiester linkages, progressing from the 3' to the 5' end. Exonuclease III plays a crucial role in DNA repair mechanisms, making it essential for studies in DNA damage response, genetic stability, and molecular biology applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 9037-44-9 |
| Applications | DNA Repair Enzyme |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.