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EXP-7711

Angiotensin II Antagonist

EXP-7711 is a non-peptide antagonist of the angiotensin II AT1 receptor, exhibiting a binding affinity (Ki) of 180 nM. While its affinity is lower than that of peptide antagonists, it surpasses that of losartan (Ki = 12 nM). This compound is utilized in research related to cardiovascular conditions, providing a valuable tool for exploring the role of the angiotensin II pathway in various cardiovascular disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	114798-27-5
Applications	Angiotensin II Antagonist
Formula	C₂₂H₂₃ClN₂O₃
Molecular Weight	398.88
SMILES	CCCCC1=NC(Cl)=C(CO)N1CC2=CC=C(C3=C(C=CC=C3)C(O)=O)C=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.