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Exserohilone

Anti-skin Aging Agent

Exserohilone, a thiodiketopiperazine derivative, functions primarily as an anti-skin aging agent by inhibiting TNF-α-induced reactive oxygen species (ROS) generation and matrix metalloproteinase-1 (MMP-1) secretion. It effectively enhances the secretion of procollagen type I α1 in human dermal fibroblasts, supporting skin structure and elasticity. This compound is valuable for exploring mechanisms of skin aging and potential therapeutic strategies for skin rejuvenation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	99572-22-2
Applications	Anti-skin Aging Agent
Formula	C₂₀H₂₂N₂O₆S₂
Molecular Weight	450.53
Synonyms	(-)-Exserohilone
SMILES	CS[C@@]12N(C([C@@]3(N([C@]4([H])[C@@](C(C=C[C@H]4O)=O)([H])C3)C2=O)SC)=O)[C@]5([H])[C@@](C(C=C[C@H]5O)=O)([H])C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.