Fig. 1 · Structure
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Ezetimibe-13C6
Stable Isotope
Ezetimibe-13C6 is a stable isotope-labeled derivative of Ezetimibe, designed for use as a tracer in metabolic studies. Ezetimibe functions as a selective inhibitor of cholesterol absorption by targeting the Niemann-Pick C1-like 1 (NPC1L1) transporter, which plays a crucial role in lipid metabolism. This compound is valuable for research applications in studying cholesterol homeostasis and metabolic disorders, as well as for exploring its effects on Nrf2 activation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 438624-68-1 |
| Applications | Stable Isotope |
| Formula | C1813C6H21F2NO3 |
| Molecular Weight | 415.38 |
| Synonyms | SCH 58235-13C6 |
| SMILES | O[C@H](C1=CC=C(C=C1)F)CC[C@@H]2[C@@H]([13C]3=[13CH][13CH]=[13C]([13CH]=[13CH]3)O)N(C4=CC=C(C=C4)F)C2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.