Fig. 1 · Structure

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Ezetimibe-d4

Stable Isotope

Ezetimibe-d4 is a stable isotope-labeled variant of Ezetimibe, a potent inhibitor of cholesterol absorption. By targeting the Niemann-Pick C1-like 1 (NPC1L1) protein, Ezetimibe-d4 effectively reduces intestinal cholesterol uptake, making it a valuable tool in lipid metabolism research. Additionally, this compound serves as an Nrf2 activator, highlighting its utility in studies related to oxidative stress and cellular defense mechanisms.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1093659-90-5
Applications Stable Isotope
Formula C24H17D4F2NO3
Molecular Weight 413.45
Synonyms SCH 58235-d4
SMILES
O=C1[C@H](CC[C@H](O)C2=CC=C(F)C=C2)[C@@H](C3=CC=C(O)C=C3)N1C(C([2H])=C4[2H])=C([2H])C([2H])=C4F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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