Fig. 1 · Structure
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Ezetimibe hydroxy glucuronide
Ezetimibe Metabolite
Ezetimibe hydroxy glucuronide is a key metabolite of Ezetimibe, primarily formed through glucuronidation. This compound is important for studying the pharmacokinetics and bioavailability of Ezetimibe in both human and canine plasma samples. Its detection provides valuable insights into the metabolic pathways and efficacy of lipid-lowering therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 536709-33-8 |
| Applications | Ezetimibe Metabolite |
| Formula | C30H29F2NO9 |
| Molecular Weight | 585.55 |
| Synonyms | SCH 488128; Ezetimibe hydroxy β-D-Glucuronide |
| SMILES | O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1O[C@H](C2=CC=C(F)C=C2)CC[C@@H]3[C@@H](C4=CC=C(O)C=C4)N(C5=CC=C(F)C=C5)C3=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.