F-1
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
Not your Region? View all Distributors
Discription | F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways, with IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively. |
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Catalog Num | A19269 |
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Formula | C22H27ClN8O3S |
Molecular Weight | 519.02 |
CAS Number | 2244775-31-1 |
SMILES | O=S(NC1=C(NC2=NC(NC3=C(OC)N=C(N4CCN(C)CC4)C=C3)=NC=C2Cl)C=CC=C1)(C)=O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2