Fig. 1 · Structure
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F-1394
ACAT Inhibitor
F-1394 is an orally active acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, designed to impede dietary cholesterol absorption. This compound exhibits significant biological activity in reducing cholesterol levels and is widely applied in cardiovascular disease research. F-1394 provides valuable insights into cholesterol metabolism and the potential therapeutic strategies for related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 162490-89-3 |
| Applications | ACAT Inhibitor |
| Formula | C33H61N3O6 |
| Molecular Weight | 595.85 |
| SMILES | CCCCCCCCCN(CC(C)(C)C)C(N[C@@H](CCCC1)[C@H]1OC(CCNC([C@H]2C(C)(COC(C)(C)O2)C)=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.