Fig. 1 · Structure
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F-17
Virulence Factor Inhibitor
F-17 is an inhibitor of virulence factors, targeting biofilm formation and other pathogenic behaviors. It demonstrates a significant inhibitory effect on biofilm production, elastase activity, pyocyanin production, and swarming motility. F-17 exhibits strong binding affinity for LasR and PqsR, crucial regulators of virulence in Pseudomonas aeruginosa, while exhibiting minimal cytotoxicity. This compound is valuable for research applications aimed at understanding and mitigating bacterial virulence.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1572464-22-2 |
| Applications | Virulence Factor Inhibitor |
| Formula | C17H15BrO4 |
| Molecular Weight | 363.20 |
| SMILES | O=C(OCCC1=CC=C(Br)C=C1)/C=C/C2=CC=C(O)C(O)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.