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F1-RIBOTAC

Ribonuclease-Targeting Chimeras

F1-RIBOTAC is a ribonuclease-targeting chimera (RIBOTAC) that functions by enhancing the activity of RNase L to selectively degrade QSOX1-a mRNA. This targeted approach results in a significant reduction in QSOX1-a expression, making F1-RIBOTAC a valuable tool for cancer research. Its design integrates RNA ligands and RNase L ligands, providing a novel modality for studying RNA degradation pathways in malignant cells.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3019907-96-8
Applications	Ribonuclease-Targeting Chimeras
Formula	C₄₉H₅₃Cl₂N₃O₁₀S
Molecular Weight	946.93
SMILES	OC(C=C(C=C1)/C=C2C(C(C(OCC)=O)=C(S/2)NC3=CC=CC=C3)=O)=C1OCCOCCOCCOCCNC(CCC(N([C@@H]4C5=CC=CC=C5[C@H](C6=CC(Cl)=C(C=C6)Cl)CC4)C)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.