Fig. 1 · Structure

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F3 peptide

Nucleolin Ligand

F3 peptide is a specific ligand for nucleolin, a protein commonly expressed on the surface of cancer cells, neovasculature, and endothelial cells. This peptide is derived from the human high mobility group protein 2 (HMGB2) and enhances the delivery of macromolecular drugs and nanoparticles. Its ability to selectively bind to nucleolin makes F3 peptide a valuable tool in cancer research and targeted therapeutic development.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 536971-53-6
Applications Nucleolin Ligand
Formula C152H263N49O41
Molecular Weight 3433.02
SMILES
C(=O)(N1[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(=O)N3[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N5[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CCCCN)=O)C)=O)CCC5)C)=O)CCCCN)=O)CCCCN)=O)CCC4)CCCCN)=O)CCC3)CCC(O)=O)=O)CCC2)CCCCN)=O)CCC1)[C@H]6N(C([C@@H](NC(=O)[C@H]7N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]8N(C([C@@H](NC([C@@H](NC([C@H](CCCCN)N)=O)CC(O)=O)=O)CCC(O)=O)=O)CCC8)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CO)=O)C)=O)CCCNC(=N)N)=O)CC(C)C)=O)CO)=O)C)=O)CCCCN)=O)CCC7)C)=O)CCC6

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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