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F3 peptide

Catalog No.: A38500
Nucleolin Ligand
F3 peptide is a specific ligand for nucleolin, a protein commonly expressed on the surface of cancer cells, neovasculature, and endothelial cells. This peptide is derived from the human high mobility group protein 2 (HMGB2) and enhances the delivery of macromolecular drugs and nanoparticles. Its ability to selectively bind to nucleolin makes F3 peptide a valuable tool in cancer research and targeted therapeutic development.
F3 peptide 536971-53-6 Nucleolin Ligand
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionF3 peptide is a specific ligand for nucleolin, a protein commonly expressed on the surface of cancer cells, neovasculature, and endothelial cells. This peptide is derived from the human high mobility group protein 2 (HMGB2) and enhances the delivery of macromolecular drugs and nanoparticles. Its ability to selectively bind to nucleolin makes F3 peptide a valuable tool in cancer research and targeted therapeutic development.
Product Information
Catalog NumA38500
FormulaC152H263N49O41
Molecular Weight3433.02
CAS Number536971-53-6
SequenceLys-Asp-Glu-Pro-Gln-Arg-Arg-Ser-Ala-Arg-Leu-Ser-Ala-Lys-Pro-Ala-Pro-Pro-Lys-Pro-Glu-Pro-Lys-Pro-Lys-Lys-Ala-Pro-Ala-Lys-Lys
Sequence shorteningKDEPQRRSARLSAKPAPPKPEPKPKKAPAKK
SMILESC(=O)(N1[C@H](C(N[C@H](C(=O)N2[C@H](C(N[C@H](C(=O)N3[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N5[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCCN)C(O)=O)=O)CCCCN)=O)C)=O)CCC5)C)=O)CCCCN)=O)CCCCN)=O)CCC4)CCCCN)=O)CCC3)CCC(O)=O)=O)CCC2)CCCCN)=O)CCC1)[C@H]6N(C([C@@H](NC(=O)[C@H]7N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]8N(C([C@@H](NC([C@@H](NC([C@H](CCCCN)N)=O)CC(O)=O)=O)CCC(O)=O)=O)CCC8)CCC(N)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CO)=O)C)=O)CCCNC(=N)N)=O)CC(C)C)=O)CO)=O)C)=O)CCCCN)=O)CCC7)C)=O)CCC6
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