Fig. 1 · Structure
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F4-Trp
α3β4 nAChR Ligand
F4-Trp (4,5,6,7-Tetrafluoro-L-tryptophan) is a selective ligand for the α3β4 nicotinic acetylcholine receptor (α3β4 nAChR). This compound exhibits significant activity in modulating neurotransmission and is valuable for studying addiction and related neurological disorders. F4-Trp serves as a critical tool for researchers investigating the intricate mechanisms of receptor function and the pathophysiology of associated diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 72120-72-0 |
| Applications | α3β4 nAChR Ligand |
| Formula | C11H8F4N2O2 |
| Molecular Weight | 276.19 |
| Synonyms | 4,5,6,7-Tetrafluoro-L-tryptophan |
| SMILES | C([C@@H](C(O)=O)N)C=1C=2C(=C(F)C(F)=C(F)C2F)NC1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.