Fig. 1 · Structure
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Factor B-IN-4
Factor B Inhibitor
Factor B-IN-4 is a potent inhibitor of complement factor B, exhibiting an IC50 of 1 μM. This compound is valuable for the investigation of diseases associated with inflammation and immune responses, making it a crucial tool for researchers studying the complement system and its role in various pathologies. Its application in research may contribute to the development of therapeutic strategies targeting inflammatory and autoimmune conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2760669-84-7 |
| Applications | Factor B Inhibitor |
| Formula | C27H32N2O4 |
| Molecular Weight | 448.55 |
| SMILES | CCO[C@H]1CCN([C@@H](C1)C2=CC=C(C=C2)C(O)=O)CC3=C(C=C(C4=C3C=CN4)C5CC5)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.